The physiological thrombocytopenia of pregnancy is mild and has no adverse effects for the mother and fetus. By contrast, a significant thrombocytopenia associated with medical conditions can have serious maternal-fetal consequences and requires specific monitoring and appropriate management.
Can low platelets affect pregnancy?
When you have too few platelets during pregnancy, called thrombocytopenia, it can cause excessive bleeding, premature delivery, or inability to get an epidural.
What is the most common cause of thrombocytopenia in pregnancy?
Gestational thrombocytopenia (defined as a mild thrombocytopenia, occurring during the 3 rd trimester with spontaneous resolution postpartum and no neonatal thrombocytopenia) is the most common cause of thrombocytopenia during pregnancy but a low platelet can also be associated with several diseases, either pregnancy …
Can low platelets cause miscarriage?
It has been reported that platelet aggregation and thrombosis during early placental development can cause miscarriage, and this can be associated with high MPV values .
Is thrombocytopenia common during pregnancy?
A mild thrombocytopenia is relatively frequent during pregnancy and has generally no consequences for either the mother or the fetus. Although representing no threat in the majority of patients, thrombocytopenia may result from a range of pathologic conditions requiring closer monitoring and possible therapy.
How do they treat low platelets during pregnancy?
If a woman with ITP becomes pregnant, her platelet count may drop in the third trimester, exacerbating existing symptoms. However, treatments such as intravenous immunoglobulin therapy (IVIG) or corticosteroids (such as prednisone) can be given to raise the platelet count to ensure a safe delivery.
What causes low platelets in first trimester?
What causes gestational thrombocytopenia? Gestational thrombocytopenia is caused by the natural changes occurring in your body during pregnancy. When you are expecting, your body increases its blood volume, causing hemodilution. This occurs when the blood plasma increases while the number of platelets remains the same.
When should I worry about low platelets in pregnancy?
When your count dips to between 100 million and 150 million platelets per ml of blood, your doctor will diagnose mild gestational thrombocytopenia. If your platelet count is only slightly below normal, it shouldn’t cause you or your baby any problems and you won’t need any treatment.
What are the causes of thrombocytopenia?
What causes thrombocytopenia?
- Alcohol use disorder and alcoholism.
- Autoimmune disease which causes ITP. …
- Bone marrow diseases, including aplastic anemia, leukemia, certain lymphomas and myelodysplastic syndromes.
- Cancer treatments like chemotherapy and radiation therapy.
What is a normal platelet count during pregnancy?
There is a normal drop in platelet count during pregnancy. In the first trimester, the normal count is around 250,000 and decreases to about 225,000 at delivery. Platelet counts <100,000 were rarely encountered in normal, uncomplicated pregnancies and should not generally be considered a physiologic change.
Can I have ac section with low platelets?
The generally accepted threshold for “safe” platelet count for labor and delivery is above 50,000/ul. This is based on expert consensus, with concern for possible C-section. There are reports of pregnant women delivering with lower platelet counts and no significant bleeding.
What is the most common cause of low platelet count?
Factors that can decrease platelet production include: Leukemia and other cancers. Some types of anemia. Viral infections, such as hepatitis C or HIV.